Richard Horton, for many years editor of The Lancet, examines the history of the relationship between doctor and patient, from ancient times to present day. The essays cover subjects including: the impact of modern warfare on health services; the debate over euthanasia; controversies over HIV and Aids; the human genome project; and the debate over the gay gene. Horton’s introduction explores the significance of the Hippocratic oath, with particular reference to the Harold Shipman murders.